When deciding whether to go for a 22 frets vs 24 frets fretboard the are two factors to consider:

First of all how important is the presence of the two extra frets to our playing style? The second point we should consider is that the presence of the 24th fret actually moves the neck and middle pickups position slightly away from the neck and toward the bridge.

Where once we had the neck single coil pickup or neck coil of the neck humbucker, we now have the 24th fret. In terms of sound, the additional 2 frets have a strong impact on the whole instrument taking it far from the classic 22 fret sound of guitars like Strats, Teles, and Pauls most of us love.

22 frets vs 24 frets graphic
Morphing from 22 frets to 24 frets on a Frudua GFF-MIX guitar.

Consequently the decision between 22 frets vs 24 frets must be taken on the importance that these two additional frets have on our playing style and technique and on if we are or we are not after a "vintage" kind of tone.

Guitar players who usually require 24 frets mainly tend to use the bridge pickup which is not in any way influenced by the number of frets on the fretboard.

Regarding easy access to the higher frets, this problem can be solved in different ways either by simply using a contoured neck heel joint using a though-neck solution, where the neck extends to become the central part of the body thus allowing a deeper contour at the heel.

Another way to achieve easy access to the last frets (in case you are building or assembling your own instrument) is to simply reduce the neck heel size as shown in the picture below. This solution only affects the neck and leaves the body/neck joint more solid and therefore it does not require any operation to the body while requiring only a little more craftsmanship on the neck.

By reducing the neck side of the heel by 5mm dramatically increases access
to the last frets. Pictured Tuscany '54 model.

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